Scientific Library
Welcome to our scientific library!
Explore more of our expertise, R&D findings and analytical know-how by accessing this large portfolio of documents compiling both technical and regulatory information.
Study & Technical sheets
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ELISpot
Download the full documentThe AID (Autoimmun Diagnostika) MultiSpot reader is a multifunctional imaging device designed for the analysis of enzymatic and fluorescent (FluoroSpot) based ELISpot assay
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Endotoxins and pyrogens testing
Download the full documentBacterial endotoxins and pyrogens (both endotoxins and non-endotoxin pyrogens (NEPs) from bacteria, viruses, yeasts, and molds) are critical quality attributes (CQ
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MALDI-TOF autoflex maX
Download the full documentThe autoflex maX is a matrix-assisted laser desorption ionisation (MALDI) with tandem Time-of-Flight (TOF/TOF) mass spectrometer from
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Silicone-based impurities determination in biopharmaceuticals
Download the full documentOrganosilicon-based compounds such as PDMS (low-molecular weight polydimethylsiloxane, i.e., Dimeticone, Simeticone, Antifoam A®
Scientific posters
Development of an immunogenicity method for detecting anti-EPO antibodies in human serum using Gyrolab platform
Location
European Gyrolab User Seminar 2024
Automated AAV capsid titre determination with Gyrolab xPlore: Qualification of generic methods and comparison with ELISA, SPR, and BLI platforms
Location
European Gyrolab User Seminar 2024
Therapeutic Protein Charge Variant Characterization with Intact Mass and Peptide Mapping Following Microgram Preparative Capillary Isoelectric Focusing Electrophoresis Fractionation
Location
ASMS 2024
Multi-attribute monitoring of therapeutic mRNA by LC-MS
Download the posterPublications & Application notes
Recombinant Factor C method, benefits and validation
Pyrogenic substances in pharmaceutical products can induce life threatening fever reactions. Endotoxins from Gram-negative bacteria were identified as the most prevalent and quantifiable pyrogens of concern.
Assessing Critical Quality Attributes of AAVs Including Aggregation and Capsid Load Using a Biozen dSEC-7 Column
In this application note, we highlight the ability of the Biozen dSEC-7 SEC column to reliably resolve monomers and aggregates from two AAV serotypes using SEC-MALS in addition to enabling accurate determination of capsid and DNA molar masses, particle concentration, and percentage full AAVs in t
Webinars
Webinar co-presented with Immudex
During this live webinar, entitled Evaluation of TCR-pMHC Affinity and its implication for T Cell
Adeno-associated viral vectors (AAVs) are small (~20-25 nm), non-enveloped viruses involved in the development of gene therapy protocols for
The field of therapeutic oligonucleotides has seen remarkable progress over the last years. Oligonucleotides have emerged as promising
During this webinar, organised by Waters, Arnaud Delobel presents a method to demonstrate the effective implementation of Multiple Attribute
Webinar organised by Genovis
During this webinar entitled Multiple-Attribute Monitoring in QC: alternatives to the bottom-up approach
Host-cell proteins are a major class of process-related impurities in biotherapeutics that can impact the safety and efficacy of the product
Live event organised by SelectScience
In this webinar recording, Arnaud Delobel presented the use of the BioLayer Interferometry (BLI)
Pyrogen testing is a regulatory requirement to ensure the product quality and safety of pharmaceutical products, as pyrogens can induce life
Event organised by Separation Science, in collaboration with Agilent.
In this presentation entitled Glycan Analysis in Biopharma
Antibody-drug conjugates (ADCs) are a class of drugs used in the treatment of different cancers. Unlike chemotherapy, ADCs are designed to
Biotherapeutics, such as monoclonal antibodies, bispecific antibodies, Antibody-Drug Conjugates, are complex molecules widely used in the
Webinar organised by Waters Corporation
In this webinar recording, we discussed the main challenges related to method development of size
Monoclonal antibodies (mAbs) constitute a major and fast-growing biotherapeutic class, thanks notably to their outstanding selectivity for
The production of monoclonal antibodies (mAbs) is a lengthy and complex process. It is, however, important to follow the mAb during
During this live webinar, we will outline the different analytical workflows that can be used for charge variant analysis (ion-exchange chromatography with salt or pH gradients, MS-compatible approaches, 2D-LC/MS, and icIEF) and present several case studies.
Access this 15 minutes webcast to learn more about an analytical method we have developed in our labs for the absolute quantification of proteins by ICP/MS.
Access this 15 minutes webcast to learn more about our large capacity and sound expertise in Mass Spectrometry.
Access this 45 minutes webinar to learn how ICP/MS can be used for the absolute quantification of proteins, with precision and accuracy that cannot be reached with amino acid analysis.
Access this 20 minutes webcast to learn how Quality Assistance developed an ICP-MS/MS method based on the quantification of P and S after microwave digestion to determine the P=O/P=S ratio in oligonucleotide samples.
Access this 45 minutes webinar to learn how HDX-MS can be applied throughout the development of your product to get structural information that can hardly be obtained with other techniques.
After a detailed description of the technique and its applications, case studies will be presented in the context of comparability and epitope mapping studies.
Access this 45 minutes webinar to learn how to characterise pluripotent stem cells in terms of identity and purity. The analytical performance of the methods developed have been discussed along with the presentation of experimental results obtained during method development, optimisation and/or validation.
Access this 45 minute webinar to learn how to characterise human mesenchymal stem cells in terms of identity, purity and biological activity. The analytical performance of the methods developed have been discussed along with the presentation of experimental results obtained during method development, optimisation and/or validation.
Join this 45 minute webinar to learn how to overcome the challenges usually associated to Multiplex assays and how to select the right technology for your needs.
Access this 45 minute webinar to learn how state-of-the-art LC/MS technologies can be implemented for the efficient study of therapeutic protein glycosylation using analyses optimised for each level of information you need.
Access this 45 minute webinar to learn how Surface Plasmon Resonance can be implemented in a GMP regulated environment for the comprehensive study of monoclonal antibodies and other Biologics.
Access this 45 minute webinar to learn how state-of-the-art LC/MS technologies can be implemented for the efficient study of ADCs using analyses optimised for each level of information you need.
Access this 45 minute webinar to learn how state-of-the-art LC/MS technologies can be implemented for the efficient study of monoclonal antibodies using analyses optimised for each level of information you need (from intact protein to peptides/amino acids).
Access this 30 minute webinar to learn how the Q3D guideline for EIs can be efficiently implemented for all drug substances, excipients and drug products.
Access this webinar which presented how the Q3D guideline for EIs can be efficiently implemented for all drug substances, excipients and drug products.
Although drug products issued from biotechnology have now been on the market for many years, accurate protein quantification remains a
Conferences
