PEGylated Proteins
Services
… Protein PEGylation is a great tool to improve the delivery of therapeutic proteins, but it adds a level of complexity to the product. As well as the characterisation of individual components (PEG and protein), …
Resources
… Absolute quantification of proteins ( i.e. quantification without the need for a … a very precise and very accurate absolute quantification of proteins. Compared to the reference method (amino acid … developed in our labs for the absolute quantification of proteins by ICP/MS. This method holds the potential to …
Absolute quantification of proteins by ICP/MS
Services
… sulfur determination. … Fast and accurate assay of single proteins by isotope dilution ICP/MS without the need of reference substance … Absolute quantification of proteins by ICP/MS … service …
Characterisation of proteins by MS
Services
… range of technologies to fully characterise therapeutic proteins. Whether you are interested in monoclonal … antibodies (mAbs), antibody-drug conjugates (ADCs), fusion proteins, small or large proteins, Quality Assistance has the tools to support you for the characterisation of drug substances and drug products, QC …
Resources
… can be implemented for the efficient study of therapeutic protein glycosylation using analyses optimised for each … We presented efficient and optimized approaches for the characterisation of protein glycosylation by UPLC/mass spectrometry, based on …
Protein aggregation
Services
Our webinar is online: Mass spectrometry toolkit for the characterisation of protein glycosylation
Article
… Assistance webinar Mass spectrometry toolkit for the characterisation of protein glycosylation given on July 12th at 16.00 … Due to their mode of production, therapeutic glycoproteins present complex and heterogeneous glycosylations. …
Resources
… a state-of-the-art approach for absolute quantification of proteins , to be used for both biological reference standard … as a generic approach to be easily applied for different proteins or peptides even in matrices containing low … specific protein products. … … Absolute quantification of proteins by ICP-MS/MS … resource …
Resources
… Abstract Almost 60% of commercialized pharmaceutical proteins are glycosylated. Glycosylation is considered a … as it affects the stability, bioactivity and safety of proteins. Hence, the development of analytical methods to characterise the composition and structure of glycoproteins is crucial. Currently, existing methods are …