Scientific Library: results
Scientific poster
Location
European Gyrolab User Seminar 2024
Automated AAV capsid titre determination with Gyrolab xPlore: Qualification of generic methods and comparison with ELISA, SPR, and BLI platforms
Location
European Gyrolab User Seminar 2024
Therapeutic Protein Charge Variant Characterization with Intact Mass and Peptide Mapping Following Microgram Preparative Capillary Isoelectric Focusing Electrophoresis Fractionation
Location
ASMS 2024
Analysis of therapeutic mRNA by orthogonal separation methods
Download the posterPublications & Application notes
In-depth characterisation of antibody charge variants by icIEF fractionation coupled to intact mass spectrometry and peptide mapping
Download the posterAddressing common challenges of biotherapeutic protein peptide mapping using recombinant trypsin
Download the posterWide Pore Polymeric Reversed-Phase PLRP-S Columns for mRNA Analysis
Download the posterAssessment of Squalene-Adenosine Nanoparticles in Two Rodent Models of Cardiac Ischemia-Reperfusion
Download the posterCapillary isoelectric focusing (icIEF) bridging study between iCE3 and Maurice equipment
Download the posterA new alternative tool to analyse glycosylation in pharmaceutical proteins based on infrared spectroscopy combined with nonlinear support vector regression
Download the posterQuantification of residual CHO host cell DNA in biotherapeutics in-process samples using KingFisher Flex system
Download the posterDevelopment and validation of an antibody-drug conjugate bioassay
Download the posterConference

Therapeutic Protein Charge Variants Characterisation using icIEF fractionation and MS
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Bridging Maurice with iCE3 (icIEF) and PA800+ (CGE) systems
In this presentation, Géry Van Vyncht covered the following topics:

Use of Octet in a GMP environment: constraints and applications
Discover more about the use of Octet in a GMP regulated environment.
During this presentation, Arnaud Delobel goes through different subjects:

ICP MS/MS: An innovative approach for the characterisation of therapeutic oligonucleotides
ICP-MS/MS: An Innovative Approach for the Characterisation of Therapeutic Oligonucleotides
ICP-MS/MS methodologies were developed for the characterisation of therapeutic oligonucleotides:

Characterisation of therapeutic oligonucleotides by ICP-MS/MS
Quality Assistance developed an innovative method for the absolute quantification of therapeutic oligonucleotides, as well as for the determination of phosphodiester-to-phosphorothioate (PO/PS) ratio by ICP-MS.MS.
Webinar

Multi-Attribute Monitoring at Peptide or Subunit Levels
During this webinar, organised by Waters, Arnaud Delobel presents a method to demonstrate the effective implementation of Multiple Attribute Monitoring (MAM) in a regu
Development and validation of an antibody-drug conjugate bioassay
Antibody-drug conjugates (ADCs) are a class of drugs used in the treatment of different cancers. Unlike chemotherapy, ADCs are
icIEF bridging study between iCE3 and Maurice equipment
Monoclonal antibodies (mAbs) constitute a major and fast-growing biotherapeutic class, thanks notably to their outstanding selectivity for specific targets.