Caractérisation multi-attributs des vecteurs viraux adéno-associés par SEC-MALS (Multi-angle light scattering)
Location
Paris, France
Scientific Library: results
Scientific poster
Automated AAV capsid titre determination with Gyrolab xPlore: Qualification of generic methods and comparison with ELISA, SPR, and BLI platforms
Location
European Gyrolab User Seminar 2024
Publications & Application notes
Comparison of 2 emulsion-based digital PCR systems: ddPCR from BioRad vs. dPCR from Stilla, for reliable determination of AAV genome titre
Download the posterCharacterisation of particle size distribution in Adeno-Associated Viral Vectors (AAVs) by Dynamic Light Scattering (DLS)
Download the posterImplementation and development of OCTET Red96e BLI platform
Download the posterValidation of a Monocyte Activation Test (MAT) using the PyroMAT™ kit
Download the posterQuantification of residual CHO host cell DNA in biotherapeutics in-process samples using KingFisher Flex system
Download the posterDevelopment and validation of home-made Luminex assays for the quantification of multiple cytokines in human samples
Download the posterSurface Plasmon Resonance
Download the posterWebinar
Characterisation of particle size distribution in Adeno-Associated Viral Vectors (AAVs) by Dynamic Light Scattering (DLS)
Adeno-associated viral vectors (AAVs) are small (~20-25 nm), non-enveloped viruses involved in the development of gene therapy protocols for the treatment of various diseases.
Characterisation of anti-HCP antibodies by 2D-Differential Gel Electrophoresis (2D-DIGE)
Host-cell proteins are a major class of process-related impurities in biotherapeutics that can impact the safety and efficacy of the product.
Conference
Physico-chemical characterisation of rAAV
During the conference "Challenges and Opportunities in Biotherapeutics Analytics", Damien Mouvet presented on the physico-chemical characterisation of rAAV. Download the slides to explore the topics and case studies he presented: