Peptide Mapping
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… analysis (ID-ICP-QQQ) of sulphur, for the quantification of proteins, including antibodies and ADCs. The method , which …
WEBINAR: Absolute quantification of mAbs and ADCs: forget amino acid analysis and shift to the new gold standard
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… to the new gold standard Absolute quantification of proteins ( i.e. quantification without the need for a … be obtained, which provides a reliable quantification of proteins and determination of extinction coefficients. … how ICP/MS can be used for the absolute quantification of proteins, with precision and accuracy that cannot be reached …
KingFisher Flex
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… is a device that automatically processes nucleic acids, proteins or cell samples . The system offers rapid and reproducible purification of high-quality DNA, RNA, proteins and cells for various types of applications. … residual host cell DNA (CHO, E.coli, HEK,…) or host cell proteins (CHO HCP or protein A) in pharmaceutical products. …
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… Host-cell proteins are a major class of process-related impurities in … . This webcast describes an alternative approach for the characterisation of the HCP coverage of these anti-HCP … be used for routine testing of residual HCPs in therapeutic proteins is appropriate. Compared to traditional Western …
Always at the forefront of analytical sciences
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… amongst which: Molecular weight determination (for mAbs , ADCs , oligonucleotides , peptides and vaccines ) Glycan …
2D UPLC/MS
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Mass spectrometry as a powerful tool for the characterisation of monoclonal antibodies in the context of comparability studies
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… spectrometry is to measure the molecular mass of the intact protein. This test can provide useful information on the identity of the protein, but also on the main glycosylation profile. Characterisation of intact antibodies The sample is first …