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… Therapeutic Protein Charge Variants Characterisation using icIEF fractionation and MS … resource …
Resources
… A novel trypsin for accurate characterisation of biotherapeutic proteins with peptide mapping … resource …
Quality Assistance acquires a SoloVPE system
Article
… variability. Speed up the development of your NBEs , ADCs , mAbs and Proteins and partner with the one-stop shop for …
Fast and accurate absolute-quantification by ICP-MS
Article
… a fast and accurate method for absolute-quantification of proteins and antibodies using Isotope Dilution -Triple … with them. Fast and accurate absolute-quantification of proteins and antibodies using Isotope Dilution-Triple … of many elements, enabling quantification of metalloproteins and peptides through the use of isotope dilution …
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… Host-cell proteins are a major class of process-related impurities in … . This webcast describes an alternative approach for the characterisation of the HCP coverage of these anti-HCP … be used for routine testing of residual HCPs in therapeutic proteins is appropriate. Compared to traditional Western …
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… Absolute quantification of proteins ( i.e. quantification without the need for a … be obtained, which provides a reliable quantification of proteins and determination of extinction coefficients. … how ICP/MS can be used for the absolute quantification of proteins, with precision and accuracy that cannot be reached …
Glycosylation
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… Recombinant proteins are increasingly used as therapeutics, and they form a large subset of the best-selling drugs. Their characterisation, from development to post-marketing quality … most prominent PTM in terms of occurrence and alteration of protein function. Adequate glycosylation is critical for …
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… for each level of information you need (from intact protein to peptides/amino acids). Analytical performance of … is a very powerful technique widely used for the characterisation of biopharmaceuticals. Thanks to … antibodies, based on three levels of analysis: Intact protein, mAb substructures (after IdeS / FabRICATOR …