Scientific Library: results

Conference

Quality-Assistance-Conference-2D LCMS

2D-LC/MS in a regulated biopharma environment: challenges and applications

In this presentation, held during the 14th Multidimensional Chromatography Working, Arnaud Delobel covered the following topics:

Authors
Arnaud Delobel
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Quality-Assistance-Conference-Bridging Maurice with ICE3 and PA800 +

Bridging Maurice with iCE3 (icIEF) and PA800+ (CGE) systems

In this presentation, Géry Van Vyncht covered the following topics:

Authors
Géry Van Vyncht
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2D LC MS Proteins Quality Assistance SEP2021

Innovative 2D-LC/MS approaches for the analysis of therapeutic proteins in a regulated environment

Discover more about our applications of 2D-LC/MS at Quality Assistance and how those systems can be used in regulated environments for the characterisation of biotherapeutics.

Authors
Dr. Arnaud Delobel
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Quality Assistance waters dublin webaf

Multiple Heartcut 2D-LC/MS: a powerful tool for biopharma analysis in a regulated environment

Multiple Heartcut 2D-LC/MS is a powerful tool for biopharma analysis in a regulated environment.
Authors
Dr Arnaud Delobel, R&D Director
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Adebiotech AATP Proteins Delobel Quality Assistance

Structural characterisation and epitope mapping by HDX-MS

Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) is an innovative tool for the characterisation of biotherapeutics.
Authors
Dr Arnaud Delobel
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Webinar

Quality-Assistance-2D-DIGE

Characterisation of anti-HCP antibodies by 2D-Differential Gel Electrophoresis (2D-DIGE)

Host-cell proteins are a major class of process-related impurities in biotherapeutics that can impact the safety and efficacy of the product.

Authors
Fabian Vandermeers
Alix Verret
Nicolas Trinchero
Arnaud Delobel
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Octet-Quality-Assistance

BioLayer Interferometry (BLI) technology as an alternative to Surface Plasmon Resonance (SPR) in biopharma regulated environment

Live event organised by SelectScience 

Authors
Arnaud Delobel
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Quality-Assistance-Elisa

Pyrogens detection using Monocyte Activation Test (MAT)

Pyrogen testing is a regulatory requirement to ensure the product quality and safety of pharmaceutical products, as pyrogens can induce life threatening fever reactions. The reference method for endotoxin testing is the in vitro Limulus Amoebocyte Lysate (LAL) assay (Ph.

Authors
Fabian Vandermeers
Sara Hully
Paula Paci
Arnaud Delobel
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icIEF bridging study between iCE3 and Maurice equipment

Monoclonal antibodies (mAbs) constitute a major and fast-growing biotherapeutic class, thanks notably to their outstanding selectivity for specific targets.

Authors
Claire Butré
Vanessa Tavernier
Didier Uwitonze
Arnaud Delobel
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Absolute quantification of proteins: forget amino acid analysis and shift to the new gold standard

Access this 15 minutes webcast to learn more about an analytical method we have developed in our labs for the absolute quantification of proteins by ICP/MS.
Authors
Dr. Arnaud Delobel
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Mass Spectrometry protein characterisation at Quality Assistance

Access this 15 minutes webcast to learn more about our large capacity and sound expertise in Mass Spectrometry.
Authors
Dr. Arnaud Delobel
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Absolute quantification of mAbs and ADCs: forget amino acid analysis and shift to the new gold standard

Access this 45 minutes webinar to learn how ICP/MS can be used for the absolute quantification of proteins, with precision and accuracy that cannot be reached with amino acid analysis.
Authors
Dr Arnaud Delobel
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HDX-MS a powerful tool for biopharmaceutical characterisation

Access this 45 minutes webinar to learn how HDX-MS can be applied throughout the development of your product to get structural information that can hardly be obtained with other techniques. After a detailed description of the technique and its applications, case studies will be presented in the context of comparability and epitope mapping studies.
Authors
Dr Arnaud Delobel
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Scientific poster

A novel trypsin for accurate characterisation of biotherapeutic proteins with peptide mapping

Authors
Thomas Menneteau
Claire I. Butré
Alba Katiria González Rivera
Sergei Saveliev
Marjeta Uhr
Arnaud Delobel
Location
ASMS Conference on Mass Spectrometry and Allied Topics
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Publications & Application notes

Validation of a Monocyte Activation Test (MAT) using the PyroMAT™ kit

Authors
Sara Hully
Fabian Vandermeers
Vincent Bertholet
Géry Van Vyncht
Arnaud Delobel
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Capillary isoelectric focusing (icIEF) bridging study between iCE3 and Maurice equipment

Authors
Vanessa Tavernier
Claire Butré
Arnaud Delobel
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Development and validation of home-made Luminex assays for the quantification of multiple cytokines in human samples

Authors
Sandra Thys
Fabian Vandermeers
Arnaud Delobel
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