[Live Webinar] Evaluation of TCR-pMHC Affinity and its Implications for T Cell Therapies
Online

 

 Evaluation of TCR-pMHC Affinity and its implication for T Cell Therapies

 

This webinar, in partnership with Immudex, will cover: 

  • Challenges associated with production of high quality TCR monomers suitable for TCR affinity measurement 
  • The importance of TCR affinity measurement in the context of development of T cell therapies 
  • Introduction to two techniques used for affinity measurement: Surface Plasmon Resonance and Biolayer Interferometry, and the pros/cons of each technique 
  • Results of a case study investigating the interaction between a modified affinity-enhanced TCR targeting the NY-ESO I antigen and its cognate pMHC (HLA-A*0201 / SLLMWITQC) in terms of affinity and kinetics 
  • Recommendations on best practices for TCR-pMHC affinity measurement

 

 

 

Speakers:

Lyn Zhu - R&D Scientist at Immudex
Fabian Vandermeers - R&D Technical Leader at Quality Assistance


Discover more on our partenership on TCR Affinity Measurement Services with Immudex