TIDES Europe
Brussels + Online
You're looking for a reliable analytical partner?
We are a benchmark CRO when it comes to analytical development and extensive experience in:
Development and validation of analytical methods for:
Quality - CMC:
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Characterisation
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Stability studies
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Batch testing
Safety & Efficacy - Bioanalysis:
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PK
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Immunogenicity
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Biomarker studies
Quality Assistance holds a unique position on the market with all its laboratories on one site, 220 highly qualified professionals and over 35 years' expertise at the forefront of analytical sciences.
We are experts in...
OLIGONUCLEOTIDES
Due to their relatively large size as compared to typical small molecule drugs, there are many technical challenges associated with the analysis of oligonucleotides. With a highly experienced staff and state-of-the-art premises and equipment, Quality Assistance is your partner of choice to overcome your analytical hurdles and facilitate the registration process.
PEPTIDES
Therapeutic peptides are at the crossroads of small molecules and proteins, requiring specific analytical packages depending on whether they are of recombinant or synthetic origin. Quality Assistance provides customised solutions in terms of analytical protocols and innovative technologies to help you move your peptide through non-clinical and clinical development towards registration.
Did you miss this event? It's not too late to catch up!
Dr. Arnaud Delobel, R&D Director at Quality Assistance, was the chairperson of the Analytical Strategies for Oligonucleotides, Peptides and mRNA Products workshop.
Access Damien Mouvet's presentation on ICP-MS/MS: an innovative approach for the characterisation of therapeutic oligonucleotides
ICP-MS/MS methodologies were developed for the characterisation of therapeutic oligonucleotides:
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Absolute quantification based on phosphorus determination
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Phosphorothioate-to-phosphodiester ratio by simultaneous determination of sulfur and phosphorus
The performance of the methods was evaluated on both standard molecules and on therapeutic oligonucleotide samples. Excellent precision and accuracy were obtained. This approach can be considered as an excellent alternative to existing methods, and can be applied in a fully GMP-compliant environment.